Max Planck Institut of Molecular Plant Physiology

PROfile analysis by Mutual Information

comparison and evaluation of functional patterns in proteinsequences

PROMI has been retired since 01.01.2021

see also: Bioinformatics at the MPI-MP

This site has been established to measure structural and functional distinction between sequences of proteins. This approach is tackled by adapting a statistical approach using mutual information (MI), a measure of association to reveal group-specific characteristics of conserved sequence motifs. In this environment group-specificity may be understood as: specificity by species, by phylogeny, by position or by any other user definition. The current stage of this service may be seen as a proof of concept, rather than a high performance high throughput tool.

For more information, you can also see the paper on PROMI in BMC Bioinformatics entiteld "Species-specific analysis of protein sequence motifs using mutual information".