Max Planck Institut of Molecular Plant Physiology

PROfile analysis by Mutual Information

comparison and evaluation of functional patterns in proteinsequences

This site has been established to measure structural and functional distinction between sequences of proteins. This approach is tackled by adapting a statistical approach using mutual information (MI), a measure of association to reveal group-specific characteristics of conserved sequence motifs. In this environment group-specificity may be understood as: specificity by species, by phylogeny, by position or by any other user definition. The current stage of this service may be seen as a proof of concept, rather than a high performance high throughput tool.

For more information, you can also see the paper on PROMI in BMC Bioinformatics entiteld "Species-specific analysis of protein sequence motifs using mutual information".

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